Description :

The book begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events the second part of the book covers the discovery of protein targets and the characterisation of toxicant protein interactions. The book begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events the second part of the book covers the discovery of protein targets and the characterisation of toxicant protein interactions. Computational toxicology is especially important for determining hazards of regulated environmental stressors and for designing safe drugs the goal of this special issue is to bring together recent developments in this field with equal emphasis given to methodological developments such as statistical approaches modeling advances and computational resources as well as applications and case . book computational systems pharmacology and toxicology issues in toxicology uploaded by david baldacci the network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments computational approaches have the potential to improve toxicological experimental design enable more rapid drug efficacy and safety testing and also reduce the number of animals used